Novo Nordisk and Netflix decline before the market; Eli Lilly and Domino's Pizza rise

LootboxPhobia · 2026-02-23T23:29:26+00:00

U.S. stock index futures slightly declined as investors react to trade uncertainties. Novo Nordisk's stock plummeted 13%, while Eli Lilly's stock rose 2.9%. Alphabet received an upgrade and its stock increased, Nvidia's stock dipped slightly. Domino's Pizza and Merck & Co. also rose, while Netflix fell due to political factors. Arcellx's stock soared 78%, and Gilead Sciences' stock declined slightly.

LootboxPhobia

2026-02-23 23:29:26

Abstract generation in progress

Investing.com - U.S. stock index futures edged lower on Monday as investors digest renewed trade uncertainties following the Supreme Court’s emergency ruling on President Trump’s tariffs.

Here are some of the biggest pre-market movers in the U.S. stock market today:

Novo Nordisk (NYSE:NVO) stock plunged over 13% after the pharmaceutical giant announced that its experimental obesity drug CagriSema failed to meet the primary endpoint in an open-label head-to-head trial.
Eli Lilly (NYSE:LLY) stock rose 2.9% after its obesity drug outperformed competitor Novo Nordisk’s drug in a Copenhagen trial.
Alphabet (NASDAQ:GOOGL) stock increased 0.3% after Wells Fargo upgraded the tech giant’s rating from “Hold” to “Overweight,” citing its advantages in data, distribution, and computing power, which could lead the next phase of AI development.
Nvidia (NASDAQ:NVDA) stock declined 0.2% as the world’s largest market cap company prepares to release earnings, potentially offering key insights into the AI sector amid growing investor skepticism.
Domino’s Pizza (NASDAQ:DPZ) stock rose 4.9% after the fast-food chain’s U.S. same-store sales in the fourth quarter exceeded expectations, driven by value-based promotions and new menu items boosting demand.
Merck & Co. (NYSE:MRK) stock increased 0.4% following a Wall Street Journal report that the pharmaceutical giant is splitting its human health business into two units to offset pressure from the patent expiration of its best-selling drug Keytruda.
Netflix (NASDAQ:NFLX) stock fell 0.7% after President Trump called for the streaming service to dismiss board member Susan Rice, warning of “consequences,” and Rice had previously stated that Democrats would push for corporate accountability if they regain control in the November midterms. The U.S. Department of Justice is currently reviewing Netflix’s proposed acquisition of Warner Bros. Discovery (NASDAQ:WBD).
Arcellx (NASDAQ:ACLX) stock surged 78%, while Gilead Sciences (NASDAQ:GILD) stock declined 0.6%, after Gilead announced it would acquire the cancer therapy developer for an implied equity value of $7.8 billion.

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