AstraZeneca’s DURGA-4 CAR-T Study Puts New Pressure on Multiple Myeloma Rivals

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AstraZeneca (GB:AZN) has announced an update on its DURGA-4 Phase 3 clinical study for AZD0120, a dual-target CAR-T cell therapy for relapsed refractory multiple myeloma. The study, which commenced in January 2026 and is actively recruiting, compares AZD0120 against standard drug regimens. Positive results could bolster AstraZeneca’s oncology portfolio, intensify competition for rivals like Johnson & Johnson and Bristol Myers Squibb, and validate dual-target CAR-T platforms.

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