All Eyes On Vertex’s Kidney Franchise, as Painkiller Journavx Tops Half a Million Scripts

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Analysts are closely observing Vertex Pharmaceuticals’ kidney disease portfolio, particularly the IgAN drug povetacicept, as its late-stage RAINIER study is progressing smoothly with data expected in the first half of 2026. While the company’s nonopioid painkiller Journavx is seeing incremental growth, competition is heating up in the IgAN space. Vertex also plans to expand povetacicept’s use into neurology for generalized myasthenia gravis, despite growing competition in that area.

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